Iridium-catalyzed selective amination of B(4)–H for the synthesis of o-carborane-fused indolines

Abstract

An iridium-catalyzed selective amination of B(4)–H via dehydrogenative cross-coupling of B–H/N–H bonds for the synthesis of o-carborane-fused indolines has been developed for the first time. Various types of unprecedented o-carborane-fused indolines have been synthesized, which would be potential candidates for applications in drug discovery, pharmaceutical chemistry and functional materials. This work offers a valuable reference for the designing and synthesis of o-carborane-fused heterocycles.