Issue 22, 1973

Observations on the mechanism of the Pictet-Gams reaction

Abstract

N-Acyl derivatives of 2-amino-I-phenylpropan-1-ol cyclise either to oxazolines or isoquinolines and since the oxazolines are readily converted into isoquinolines, their intermediacy in the Pictet–Gams reaction is postulated.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1973, 889-890

Observations on the mechanism of the Pictet-Gams reaction

A. O. Fitton, J. R. Frost, M. M. Zakaria and G. Andrew, J. Chem. Soc., Chem. Commun., 1973, 889 DOI: 10.1039/C39730000889

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