A convenient enantiospecific total synthesis of (–)-11-nor-Δ9-tetrahydrocannabinol-9-methanol, a human urinary metabolite of Δ9-tetrahydrocannabinol, has been accomplished in six steps from (R)-(+)-perillaldehyde.
M. A. Tius, X. Gu and M. A. Kerr, J. Chem. Soc., Chem. Commun., 1989, 62 DOI: 10.1039/C39890000062
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