Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.
J. L. J. Dearling and P. J. Blower, Chem. Commun., 1998, 2531 DOI: 10.1039/A805957H
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