An external chiral tridentate amino diether ligand 7 catalyzed the condensation reaction of a lithium ester enolate 2 with an imine 3 to give the enantiomerically enriched β-lactam 4 in high yield.
K. Tomioka, M. Ahmed Hussein, T. Kambara, H. Fujieda, S. Hayashi, Y. Nomura, M. Kanai and K. Koga, Chem. Commun., 1999, 715 DOI: 10.1039/A901424A
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