The total synthesis of the β-lactone cholesterol synthase inhibitor 1233A (1) is described employing the oxidative decomplexation of a (π-allyl)tricarbonyliron lactone (2) as the key synthetic step.
R. W. Bates, E. Fernández-Megía, S. V. Ley, K. Rück-Braun and D. Matthew G. Tilbrook, J. Chem. Soc., Perkin Trans. 1, 1999, 1917 DOI: 10.1039/A903641E
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