Issue 5, 2000
From the journal:

Chemical Communications

Chemoselective oxidative debenzylation of tertiary N-benzyl amines

Steven D. Bull,a   Stephen G. Davies,*a   Garry Fenton,b   Andrew W. Mulvaney,a   R. Shyam Prasada  and  Andrew D. Smitha  

* Corresponding authors

a The Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford, UK
E-mail: steve.davies@chem.ox.ac.uk

b Rhône-Poulenc Rorer, Rainham Road South, Dagenham, Essex, UK

Abstract

Treatment of tertiary amines containing one or more N-benzyl protecting groups with aqueous ceric ammonium nitrate results in clean N-debenzylation to afford the corresponding secondary amine.

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Article information

DOI
https://doi.org/10.1039/B000071J
Article type
Communication
Submitted
04 Jan 2000
Accepted
25 Jan 2000
First published
21 Feb 2000

Chem. Commun., 2000, 337-338

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Chemoselective oxidative debenzylation of tertiary N-benzyl amines

S. D. Bull, S. G. Davies, G. Fenton, A. W. Mulvaney, R. S. Prasad and A. D. Smith, Chem. Commun., 2000, 337 DOI: 10.1039/B000071J

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