The 1:1 intermediate generated by the additon of cyclohexyl isocyanide to dimethyl acetylenedicarboxylate is trapped by aldehydes to yield 2-aminofuran derivatives in good yields.
The reaction of cyclohexyl isocyanide and dimethyl acetylenedicarboxylate with aldehydes: a novel synthesis of 2-aminofuran derivatives
V. Nair and A. U. Vinod, Chem. Commun., 2000, 1019 DOI: 10.1039/B001698P
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