Issue 22, 2001

Multi-component coupling reactions: synthesis of a guanidine containing analog of the hexahydropyrrolo[3,2-c]quinoline alkaloid martinelline

Abstract

A multi-component coupling reaction is used to synthesize a highly functionalized guanidine containing pyrroloquinoline analog of martinelline that displays bradykinin B2 receptor antagonist activity.

Graphical abstract: Multi-component coupling reactions: synthesis of a guanidine containing analog of the hexahydropyrrolo[3,2-c]quinoline alkaloid martinelline

Article information

Article type
Communication
Submitted
15 Aug 2001
Accepted
19 Sep 2001
First published
24 Oct 2001

Chem. Commun., 2001, 2362-2363

Multi-component coupling reactions: synthesis of a guanidine containing analog of the hexahydropyrrolo[3,2-c]quinoline alkaloid martinelline

R. A. Batey and D. A. Powell, Chem. Commun., 2001, 2362 DOI: 10.1039/B107431H

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