This article deals with our recent studies on the synthesis of BNAs (Bridged Nucleic Acids), novel nucleic acid analogs bearing a preorganized sugar conformation by a bridged structure. Duplex- and triplex-forming abilities of the BNA modified oligonucleotides are also described.
T. Imanishi and S. Obika, Chem. Commun., 2002, 1653 DOI: 10.1039/B201557A
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