Issue 5, 2003
From the journal:

Chemical Communications

First example of electrophile induced Baylis–Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives†

Deevi Basavaiah*a  and  Anumolu Jaganmohan Raoa  

* Corresponding authors

a School of Chemistry, University of Hyderabad, Hyderabad-500 046, India
E-mail: dbsc@uohyd.ernet.in
Fax: +91-40-23012460

Abstract

Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis–Hillman reaction.

Graphical abstract: First example of electrophile induced Baylis–Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives

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Article information

DOI
https://doi.org/10.1039/B211349J
Article type
Communication
Submitted
19 Nov 2002
Accepted
13 Jan 2003
First published
17 Feb 2003

Chem. Commun., 2003, 604-605

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First example of electrophile induced Baylis–Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives

D. Basavaiah and A. Jaganmohan Rao, Chem. Commun., 2003, 604 DOI: 10.1039/B211349J

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