Issue 2, 2005
From the journal:

Chemical Communications

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA†

Anca Dragulescu-Andrasi,a   Peng Zhou,a   Gaofei Hea  and  Danith H. Ly*a  

* Corresponding authors

a Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA, USA
E-mail: dly@andrew.cmu.edu
Fax: 412 268 5579
Tel: 412 268 4010

Abstract

Guanidine-based peptide nucleic acid (GPNA) with a D-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.

Graphical abstract: Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

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Article information

DOI
https://doi.org/10.1039/B412522C
Article type
Communication
Submitted
13 Aug 2004
Accepted
15 Oct 2004
First published
02 Dec 2004

Chem. Commun., 2005, 244-246

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Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

A. Dragulescu-Andrasi, P. Zhou, G. He and D. H. Ly, Chem. Commun., 2005, 244 DOI: 10.1039/B412522C

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