A highly water-soluble C60–NVP copolymer: a potential material for photodynamic therapy

Yuko Iwamoto; Yoko Yamakoshi

doi:10.1039/B614305A

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A highly water-soluble C₆₀–NVP copolymer: a potential material for photodynamic therapy†

Yuko Iwamoto^a and Yoko Yamakoshi*^a

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* Corresponding authors

^a Department of Chemistry and Biochemistry, University of California at Santa Barbara, Santa Barbara, CA 93106-9510, USA
E-mail: yamakoshi@chem.ucsb.edu
Fax: +1 805 893 4120
Tel: +1 805 893 3638

Abstract

Water-soluble C₆₀ polymers, which have the highest solubility of fullerene reported to date (7.8 mM of C₆₀ in water), were prepared via copolymerization, and showed significant visible light-induced O₂˙⁻ generation and DNA cleavage, indicating the potential of these water-soluble fullerene derivatives as agents for photodynamic therapy.

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Supplementary files

Experimental section PDF (1291K)

Article information

DOI: https://doi.org/10.1039/B614305A
Article type: Communication
Submitted: 03 Oct 2006
Accepted: 25 Oct 2006
First published: 03 Nov 2006

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Chem. Commun., 2006, 4805-4807

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A highly water-soluble C₆₀–NVP copolymer: a potential material for photodynamic therapy

Y. Iwamoto and Y. Yamakoshi, Chem. Commun., 2006, 4805 DOI: 10.1039/B614305A

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