Issue 46, 2007
From the journal:

Chemical Communications

Efficient gene transfection with functionalised multicalixarenes†

Ruth Lalor,a   Jessica L. DiGesso,a   Anja Muellera  and  Susan E. Matthews*a  

* Corresponding authors

a School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK
E-mail: susan.matthews@uea.ac.uk
Fax: 44 1603 592003
Tel: 44 1603 593986

Abstract

Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.

Graphical abstract: Efficient gene transfection with functionalised multicalixarenes

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Article information

DOI
https://doi.org/10.1039/B712100H
Article type
Communication
Submitted
07 Aug 2007
Accepted
05 Sep 2007
First published
14 Sep 2007

Chem. Commun., 2007, 4907-4909

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Efficient gene transfection with functionalised multicalixarenes

R. Lalor, J. L. DiGesso, A. Mueller and S. E. Matthews, Chem. Commun., 2007, 4907 DOI: 10.1039/B712100H

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