Issue 1, 2007
From the journal:

Lab on a Chip

Solvent resistant microfluidic DNA synthesizer†

Yanyi Huang,‡§a   Piero Castrataro‡,ab   Cheng-Chung Lee‡ac  and  Stephen R. Quake*a  

* Corresponding authors

a Department of Bioengineering, Stanford University and Howard Hughes Medical Institute, California, USA
E-mail: quake@stanford.edu

b CRIM Laboratory, Scuola Superiore Sant'Anna, Viale R. Piaggio 34, Pontedera (PI), Italy

c Department of Bioengineering, California Institute of Technology, Pasadena, California, USA

Abstract

We fabricated a microfluidic DNA synthesizer out of perfluoropolyether (PFPE), an elastomer with excellent chemical compatibility which makes it possible to perform organic chemical reactions, and synthesized 20-mer oligonucleotides on chip.

Graphical abstract: Solvent resistant microfluidic DNA synthesizer

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Article information

DOI
https://doi.org/10.1039/B613923J
Article type
Communication
Submitted
25 Sep 2006
Accepted
20 Nov 2006
First published
30 Nov 2006

Lab Chip, 2007,7, 24-26

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Solvent resistant microfluidic DNA synthesizer

Y. Huang, P. Castrataro‡, C. Lee‡ and S. R. Quake, Lab Chip, 2007, 7, 24 DOI: 10.1039/B613923J

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