Issue 7, 2009
From the journal:

Chemical Communications

Modulating DNA adsorption on silica beads using an electrical switch†

Tao Geng,a   Ning Bao,a   Oren Z. Gallb  and  Chang Lu*acd  

* Corresponding authors

a Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, USA
E-mail: changlu@purdue.edu
Fax: +01-765-496-1115
Tel: +01-765-494-1188

b School of Electrical and Computer Engineering, Purdue University, West Lafayette, USA

c Weldon School of Biomedical Engineering, Purdue University, West Lafayette, USA

d School of Chemical Engineering, Purdue University, West Lafayette, USA

Abstract

We demonstrate active tuning of DNA adsorption on silica beads using an electrical switch in a microfluidic device; we use electrolysis of water to alter pH in a packed bed of silica beads and switch the silica bead surface between being adsorptive and desorptive for DNA molecules.

Graphical abstract: Modulating DNA adsorption on silica beads using an electrical switch

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Article information

DOI
https://doi.org/10.1039/B817034G
Article type
Communication
Submitted
29 Sep 2008
Accepted
09 Nov 2008
First published
19 Dec 2008

Chem. Commun., 2009, 800-802

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Modulating DNA adsorption on silica beads using an electrical switch

T. Geng, N. Bao, O. Z. Gall and C. Lu, Chem. Commun., 2009, 800 DOI: 10.1039/B817034G

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