Issue 6, 2010

Practical copper(i)-catalysed amidation of aldehydes

Abstract

The direct synthesis of amides by insertion into the C–H bond of aldehydes is shown to be a practical procedure through application of cheap, readily available catalysts generated in situ from copper(I) halides and pyridine.

Graphical abstract: Practical copper(i)-catalysed amidation of aldehydes

Supplementary files

Article information

Article type
Communication
Submitted
08 Sep 2009
Accepted
16 Nov 2009
First published
04 Dec 2009

Chem. Commun., 2010,46, 922-924

Practical copper(I)-catalysed amidation of aldehydes

J. W. W. Chang, T. M. U. Ton, S. Tania, P. C. Taylor and P. W. H. Chan, Chem. Commun., 2010, 46, 922 DOI: 10.1039/B918588G

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