Issue 12, 2010
From the journal:

Chemical Communications

The first isoform-selective proteinbiosensor: a metallothionein potentiometric electrode

Mercè Capdevila,†*a   Anna González-Bellavista,‡a   Maria Muñoz,§a   Sílvia Atrianb  and  Esteve Fàbregas‡a  

* Corresponding authors

a Departament de Química, Facultat de Ciències, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Barcelona, Spain
E-mail: merce.capdevila@uab.cat
Fax: +34 935813101
Tel: +34 935813323

b Departament de Genètica, Facultat de Biologia, Universitat de Barcelona and Institut de Biomedicina de la Universitat de Barcelona, Av. Diagonal 645, Barcelona, Spain

Abstract

The construction of a biosensor membrane by embedding mammalian Zn7-MT1 complexes as ionophores in a polysulfone matrix resulted in precise, accurate and, significantly, selective electrodes for MT1 quantification, so that the presence of other mammalian MT isoforms did not interfere in MT1 measurement.

Graphical abstract: The first isoform-selective proteinbiosensor: a metallothionein potentiometric electrode

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Article information

DOI
https://doi.org/10.1039/B922284G
Article type
Communication
Submitted
26 Oct 2009
Accepted
01 Feb 2010
First published
12 Feb 2010

Chem. Commun., 2010,46, 2040-2042

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The first isoform-selective proteinbiosensor: a metallothionein potentiometric electrode

M. Capdevila, A. González-Bellavista, M. Muñoz, S. Atrian and E. Fàbregas, Chem. Commun., 2010, 46, 2040 DOI: 10.1039/B922284G

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