Issue 44, 2010
From the journal:

Chemical Communications

Tandem driven dynamic self-inhibition of acetylcholinesterase†‡

Yan Zhang,a   Marcus Angelin,a   Rikard Larsson,a   Antonia Albers,a   Adrian Simonsa  and  Olof Ramström*a  

* Corresponding authors

a Department of Chemistry, KTH—Royal Institute of Technology, Teknikringen 30, Stockholm, Sweden
E-mail: ramstrom@kth.se
Fax: +46 8 7912333

Abstract

A concept of tandem driven dynamic self-inhibition is demonstrated through dynamic inhibitors of acetylcholinesterase (AChE) using reversible transthiolesterification.

Graphical abstract: Tandem driven dynamic self-inhibition of acetylcholinesterase

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Article information

DOI
https://doi.org/10.1039/C0CC02479A
Article type
Communication
Submitted
10 Jul 2010
Accepted
16 Sep 2010
First published
04 Oct 2010

Chem. Commun., 2010,46, 8457-8459

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Tandem driven dynamic self-inhibition of acetylcholinesterase

Y. Zhang, M. Angelin, R. Larsson, A. Albers, A. Simons and O. Ramström, Chem. Commun., 2010, 46, 8457 DOI: 10.1039/C0CC02479A

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