Issue 46, 2010
From the journal:

Chemical Communications

The time domain in co-stained cell imaging: time-resolved emission imaging microscopy using a protonatable luminescent iridium complex†

Lisa Murphy,a   Aileen Congreve,a   Lars-Olof Pålssona  and  J. A. Gareth Williams*a  

* Corresponding authors

a Department of Chemistry, University of Durham, Durham, UK
E-mail: j.a.g.williams@durham.ac.uk
Fax: +44 (0)191 334 2124

Abstract

The intense luminescence of the new complex Ir(ppy)2(pybz) (1) within the cytoplasm of live cells can be discriminated from the fluorescence of an organic stain, solely on the basis of the emission timescale {pybzH = 2-pyridyl-benzimidazole}. The protonated form of 1 displays red-shifted emission, and may be implicated in a superior uptake compared to Ir(ppy)3.

Graphical abstract: The time domain in co-stained cell imaging: time-resolved emission imaging microscopy using a protonatable luminescent iridium complex

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Article information

DOI
https://doi.org/10.1039/C0CC03705B
Article type
Communication
Submitted
07 Sep 2010
Accepted
01 Oct 2010
First published
21 Oct 2010

Chem. Commun., 2010,46, 8743-8745

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The time domain in co-stained cell imaging: time-resolved emission imaging microscopy using a protonatable luminescent iridium complex

L. Murphy, A. Congreve, L. Pålsson and J. A. G. Williams, Chem. Commun., 2010, 46, 8743 DOI: 10.1039/C0CC03705B

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