Issue 47, 2010
From the journal:

Chemical Communications

Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides†

Dongbing Zhao,a   Chao Gao,a   Xiaoyu Su,a   Yunqing He,a   Jingsong You*a  and  Ying Xue*a  

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, and State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, P.R. China
E-mail: jsyou@scu.edu.cn
Fax: (+86) 28-85412203

Abstract

The copper-catalyzed decarboxylative reactions of alkynyl carboxylic acids with aryl halides were performed under relatively mild reaction conditions. Benzofurans could be further prepared smoothly by a one-pot domino protocol on the basis of decarboxylative cross-coupling of 2-iodophenol.

Graphical abstract: Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides

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Article information

DOI
https://doi.org/10.1039/C0CC03772A
Article type
Communication
Submitted
10 Sep 2010
Accepted
11 Oct 2010
First published
04 Nov 2010

Chem. Commun., 2010,46, 9049-9051

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Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides

D. Zhao, C. Gao, X. Su, Y. He, J. You and Y. Xue, Chem. Commun., 2010, 46, 9049 DOI: 10.1039/C0CC03772A

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