Issue 7, 2010
From the journal:

Nanoscale

Silica-based nanoparticles for photodynamic therapy applications

Pierre Couleaud,b   Vincent Morosini,c   Céline Frochot,bd   Sébastien Richeter,a   Laurence Raehma  and  Jean-Olivier Durand*a  

* Corresponding authors

a Institut Charles Gerhardt Montpellier, UMR 5253 CNRS-UM2-ENSCM-UM1, Equipe Chimie Moléculaire et Organisation du Solide, CC1701 Place Eugène Bataillon, Montpellier Cedex 05, France
E-mail: durand@univ-montp2.fr

b Laboratoire Réactions et génie des Procédés, UPR 3349, Nancy-Université, 1, rue Grandville, Nancy, France

c Centre de Recherche en Automatique de Nancy (CRAN), UMR 7039, Nancy-Université, CNRS, Centre Alexis Vautrin, Vandœuvre-lès-Nancy, France

d GDR 3049 “Médicaments Photoactivables – Photochimiothérapie (PHOTOMED)”

Abstract

Silica-based nanoparticles for applications in photodynamic therapy (PDT) have emerged as a promising field for the treatment of cancer. In this review, based on the pathway the photosensitizer is entrapped inside the silica matrix, the different methods for the synthesis of silica-based nanoparticles are described from the pioneering works to the latest achievements which concern multifunctional nanoplatforms, up-converting nanoparticles, two-photon PDT, vectorization and in vivo applications.

Graphical abstract: Silica-based nanoparticles for photodynamic therapy applications

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Article information

DOI
https://doi.org/10.1039/C0NR00096E
Article type
Review Article
Submitted
08 Feb 2010
Accepted
18 Mar 2010
First published
25 May 2010

Nanoscale, 2010,2, 1083-1095

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Silica-based nanoparticles for photodynamic therapy applications

P. Couleaud, V. Morosini, C. Frochot, S. Richeter, L. Raehm and J. Durand, Nanoscale, 2010, 2, 1083 DOI: 10.1039/C0NR00096E

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