Design, synthesis and evaluation of β-lactam antigenic peptide hybrids; unusual opening of the β-lactam ring in acidic media†
Abstract
β-Lactam
* Corresponding authors
a
Université de Bordeaux, Institut des Sciences Moléculaires (UMR-CNRS 5255) and Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, France
E-mail:
s.quideau@iecb.u-bordeaux.fr
Fax: (+33) 5-4000-2215
Tel: (+33) 5-4000-3010
b Departamento de Química Orgánica-I, Universidad del País Vasco, Joxe Mari Korta R&D Center, Apdo. Tolosa-72, Spain
c Department of Medical Biochemistry and Immunology, Henry Wellcome Building, Cardiff University School of Medicine, Heath Park, Cardiff, UK
d Department of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, USA
β-Lactam
M. Tarbe, I. Azcune, E. Balentová, J. J. Miles, E. E. Edwards, K. M. Miles, P. Do, B. M. Baker, A. K. Sewell, J. M. Aizpurua, C. Douat-Casassus and S. Quideau, Org. Biomol. Chem., 2010, 8, 5345 DOI: 10.1039/C003877F
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