Issue 3, 2011
From the journal:

Chemical Communications

Cu(ii) catalyzed oxidation-[3+2] cycloaddition-aromatization cascade: Efficient synthesis of pyrrolo [2, 1-a] isoquinolines†

Chenguang Yu,ab   Yianan Zhang,a   Shilei Zhang,a   Hao Lic  and  Wei Wang*ac  

* Corresponding authors

a Department of Chemistry & Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, USA
E-mail: wwang@unm.edu
Fax: (+1) 505-277-2609

b State Key Laboratory of Chemical Resources Engineering, Beijing University of Chemical Technology, Beijing 100029, China

c Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

Abstract

A novel and synthetically efficient Cu(II) catalyzed oxidation-dipolar cycloaddition-aromatization cascade reaction has been developed for a “one-pot” synthesis of biologically important pyrrolo [2, 1-a] isoquinolines.

Graphical abstract: Cu(ii) catalyzed oxidation-[3+2] cycloaddition-aromatization cascade: Efficient synthesis of pyrrolo [2, 1-a] isoquinolines

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Article information

DOI
https://doi.org/10.1039/C0CC03186K
Article type
Communication
Submitted
11 Aug 2010
Accepted
18 Oct 2010
First published
12 Nov 2010

Chem. Commun., 2011,47, 1036-1038

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Cu(II) catalyzed oxidation-[3+2] cycloaddition-aromatization cascade: Efficient synthesis of pyrrolo [2, 1-a] isoquinolines

C. Yu, Y. Zhang, S. Zhang, H. Li and W. Wang, Chem. Commun., 2011, 47, 1036 DOI: 10.1039/C0CC03186K

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