Issue 7, 2011
From the journal:

Chemical Communications

A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates†

Yun Xiang,*a   Xiaoqing Qian,a   Ying Chen,a   Yuyong Zhang,a   Yaqin Chaia  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86 23-68252277
Tel: +86 23-68253172

Abstract

Reagentless, sensitive and multiplexed analysis of gyrB and K-rasgene biomarkers is achieved based on the proximity changes of two different redox-tags to the electrode surface upon DNA hybridizations, and the presence of the two gene biomarkers also acts as inputs and activates the logic gate.

Graphical abstract: A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates

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Article information

DOI
https://doi.org/10.1039/C0CC04350H
Article type
Communication
Submitted
11 Oct 2010
Accepted
07 Dec 2010
First published
04 Jan 2011

Chem. Commun., 2011,47, 2080-2082

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A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates

Y. Xiang, X. Qian, Y. Chen, Y. Zhang, Y. Chai and R. Yuan, Chem. Commun., 2011, 47, 2080 DOI: 10.1039/C0CC04350H

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