Issue 11, 2011
From the journal:

Chemical Communications

High-fidelity determination of security threats via a Boolean biocatalytic cascade†

Min-Chieh Chuang,a   Joshua Ray Windmiller,a   Padmanabhan Santhosh,a   Gabriela Valdés Ramírez,a   Evgeny Katz*b  and  Joseph Wang*a  

* Corresponding authors

a Department of Nanoengineering, University of California San Diego, La Jolla, California 92093, USA
E-mail: josephwang@ucsd.edu
Fax: +1 858 534 9553
Tel: +1 858 246 0128

b Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA
E-mail: ekatz@clarkson.edu
Fax: +1 315 268 6610
Tel: +1 315 268 4421

Abstract

The ability to assess diverse security threats using a biochemical logic network system is demonstrated. The new biocatalytic cascade, emulating a NOR logic gate, is able to identify the presence of explosive compounds and nerve agents by providing a simple and rapid ‘YES’/‘NO’ alert.

Graphical abstract: High-fidelity determination of security threats via a Boolean biocatalytic cascade

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Article information

DOI
https://doi.org/10.1039/C0CC05716A
Article type
Communication
Submitted
21 Dec 2010
Accepted
26 Jan 2011
First published
11 Feb 2011

Chem. Commun., 2011,47, 3087-3089

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High-fidelity determination of security threats via a Boolean biocatalytic cascade

M. Chuang, J. R. Windmiller, P. Santhosh, G. V. Ramírez, E. Katz and J. Wang, Chem. Commun., 2011, 47, 3087 DOI: 10.1039/C0CC05716A

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