Issue 13, 2011
From the journal:

Chemical Communications

Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin†

Cang Wang,a   Peng-Fei Ren,b   Xiao-Jun Huang,b   Jian Wua  and  Zhi-Kang Xu*b  

* Corresponding authors

a Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China
E-mail: jianwu@zju.edu.cn
Fax: 86 571 8795 1773
Tel: 86 571 8795 1052

b MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, ZhejiangUniversity, Hangzhou 310027, P. R. China

Abstract

We present a novel approach to constructing glycosylated surface for microporous membrane. Carbohydrate derivative can be facilely bound onto the alkyne-modified membrane surface viathiol-yne click chemistry. The glycosylated membrane surface shows an excellent affinity adsorption to lectin on the basis of carbohydrate–protein recognition.

Graphical abstract: Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin

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Article information

DOI
https://doi.org/10.1039/C1CC10634A
Article type
Communication
Submitted
01 Feb 2011
Accepted
08 Feb 2011
First published
24 Feb 2011

Chem. Commun., 2011,47, 3930-3932

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Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin

C. Wang, P. Ren, X. Huang, J. Wu and Z. Xu, Chem. Commun., 2011, 47, 3930 DOI: 10.1039/C1CC10634A

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