Issue 20, 2011
From the journal:

Chemical Communications

Suitability of porous silicon microparticles for the long-term delivery of redox-active therapeutics†

Elizabeth C. Wu,a   Jennifer S. Andrew,b   Alex Buyanin,c   Joseph M. Kinsellac  and  Michael J. Sailor*ac  

* Corresponding authors

a Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, USA
E-mail: msailor@ucsd.edu

b Department of Materials Science and Engineering, University of Florida, P.O. Box 116400, Gainesville, USA

c Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, USA

Abstract

Thermal oxidation of porous Si microparticles provides an inert carrier for the long-term release of the anthracycline drug daunorubicin. Without prior oxidation, porous Si undergoes an undesirable side reaction with this redox active drug.

Graphical abstract: Suitability of porous silicon microparticles for the long-term delivery of redox-active therapeutics

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC10993F
Article type
Communication
Submitted
19 Feb 2011
Accepted
28 Mar 2011
First published
18 Apr 2011

Chem. Commun., 2011,47, 5699-5701

Permissions

Request permissions

Suitability of porous silicon microparticles for the long-term delivery of redox-active therapeutics

E. C. Wu, J. S. Andrew, A. Buyanin, J. M. Kinsella and M. J. Sailor, Chem. Commun., 2011, 47, 5699 DOI: 10.1039/C1CC10993F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements