Issue 22, 2011
From the journal:

Chemical Communications

Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor†

Yue Zhao,a   Xi-Wen Hea  and  Xue-Bo Yin*a  

* Corresponding authors

a Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, P. R. China
E-mail: xbyin@nankai.edu.cn
Fax: +86-22-23502458

Abstract

Analyte-induced formation of partial duplexes was used for biosensor development with cocaine as a model. The cocaine–aptamer interaction resulted in formation of a partial double strand section in the aptamer, where Ru(phen)32+ was intercalated for electrochemiluminescent analysis of cocaine.

Graphical abstract: Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor

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Article information

DOI
https://doi.org/10.1039/C1CC11529D
Article type
Communication
Submitted
17 Mar 2011
Accepted
14 Apr 2011
First published
09 May 2011

Chem. Commun., 2011,47, 6419-6421

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Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor

Y. Zhao, X. He and X. Yin, Chem. Commun., 2011, 47, 6419 DOI: 10.1039/C1CC11529D

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