Issue 31, 2011
From the journal:

Chemical Communications

A facile, modular and high yield method to assemble three-dimensional DNA structures†‡

Christopher K. McLaughlin,a   Graham D. Hamblin,a   Faisal A. Aldaye,a   Hua Yanga  and  Hanadi F. Sleiman*a  

* Corresponding authors

a Department of Chemistry, 801 Sherbrooke St. West, Montreal, QC, Canada
E-mail: hanadi.sleiman@mcgill.ca
Fax: +1-514-398-3797
Tel: +1-514-398-2633

Abstract

We describe a rapid and quantitative method to generate DNA cages of deliberately designed geometry from readily available starting strands. Balancing the incorporation of sequence uniqueness and symmetry in a face-centered approach to 3D construction can result in triangular (TP), rectangular (RP), and pentagonal prisms (PP) without compromising the potential for nanostructure addressability.

Graphical abstract: A facile, modular and high yield method to assemble three-dimensional DNA structures

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Article information

DOI
https://doi.org/10.1039/C1CC11726B
Article type
Communication
Submitted
26 Mar 2011
Accepted
24 May 2011
First published
11 Jul 2011

Chem. Commun., 2011,47, 8925-8927

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A facile, modular and high yield method to assemble three-dimensional DNA structures

C. K. McLaughlin, G. D. Hamblin, F. A. Aldaye, H. Yang and H. F. Sleiman, Chem. Commun., 2011, 47, 8925 DOI: 10.1039/C1CC11726B

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