Issue 27, 2011
From the journal:

Chemical Communications

A regio- and stereoselective synthesis of trisubstituted alkenesviagold(i)-catalyzed hydrophosphoryloxylation of haloalkynes†

Bathoju Chandra Chary,a   Sunggak Kim,*a   Doosup Shinb  and  Phil Ho Lee*b  

* Corresponding authors

a Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore
E-mail: sgkim@ntu.edu.sg

b Department of Chemistry, Institute of Molecular Science and Fusion Technology, Kangwon National University, Chuncheon 200-701, Republic of Korea
E-mail: phlee@kangwon.ac.kr

Abstract

A new stereoselective synthesis of trisubstituted alkenes is developed. Hydrophosphoryloxylation of haloalkynes provides Z-alkenyl halophosphates, which undergo Pd-catalyzed consecutive cross-coupling reactions to afford regio- and stereodefined trisubstituted alkenes.

Graphical abstract: A regio- and stereoselective synthesis of trisubstituted alkenesviagold(i)-catalyzed hydrophosphoryloxylation of haloalkynes

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC12052B
Article type
Communication
Submitted
11 Apr 2011
Accepted
24 May 2011
First published
06 Jun 2011

Chem. Commun., 2011,47, 7851-7853

Permissions

Request permissions

A regio- and stereoselective synthesis of trisubstituted alkenesviagold(I)-catalyzed hydrophosphoryloxylation of haloalkynes

B. C. Chary, S. Kim, D. Shin and P. H. Lee, Chem. Commun., 2011, 47, 7851 DOI: 10.1039/C1CC12052B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements