Issue 29, 2011

Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

Abstract

Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives have been developed. The cascade reactions products could be obtained with three stereocenters in high yields and excellent diastereo- and enantioselectivities.

Graphical abstract: Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

Article information

Article type
Communication
Submitted
20 Apr 2011
Accepted
02 Jun 2011
First published
20 Jun 2011

Chem. Commun., 2011,47, 8325-8327

Highly diastereo- and enantioselective one-pot Michael–Aldol reactions of α,β-unsaturated aldehydes with imidazole derivatives

W. Li, X. Li, W. Wu, X. Liang and J. Ye, Chem. Commun., 2011, 47, 8325 DOI: 10.1039/C1CC12300A

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