Issue 31, 2011
From the journal:

Chemical Communications

Antibody-functionalized SERS tags with improved sensitivity†

Nekane Guarrotxena*ab  and  Guillermo C. Bazan*b  

* Corresponding authors

a Instituto de Ciencia y Tecnología de Polímeros (ICTP), Consejo Superior de Investigaciones Científicas (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain
E-mail: nekane@ictp.csic.es

b Department of Chemistry & Biochemistry and Materials, Institute for Polymers and Organic Solids, University of California, Santa Barbara, California 93106, USA
E-mail: bazan@chem.ucsb.edu

Abstract

Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain suitable surface-bound recognition elements. Proper control of the interaction between nanoparticles within the assemblies is critical for achieving this performance.

Graphical abstract: Antibody-functionalized SERS tags with improved sensitivity

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Article information

DOI
https://doi.org/10.1039/C1CC12659H
Article type
Communication
Submitted
06 May 2011
Accepted
13 Jun 2011
First published
07 Jul 2011

Chem. Commun., 2011,47, 8784-8786

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Antibody-functionalized SERS tags with improved sensitivity

N. Guarrotxena and G. C. Bazan, Chem. Commun., 2011, 47, 8784 DOI: 10.1039/C1CC12659H

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