Issue 28, 2011
From the journal:

Chemical Communications

Multiplexed near-infrared in vivo imaging complementarily using quantum dots and upconverting NaYF4:Yb3+,Tm3+ nanoparticles†

Sanghwa Jeong,a   Nayoun Won,a   Jinsik Lee,a   Jiwon Bang,a   Jeongsoo Yoo,b   Sang Geol Kim,c   Jeong Ah Chang,d   Joonghyun Kime  and  Sungjee Kim*a  

* Corresponding authors

a Department of Chemistry, Pohang University of Science and Technology, San 31, Hyoja-Dong, Nam-Gu, Pohang, South Korea
E-mail: sungjee@postech.ac.kr
Fax: +82-54-279-1498
Tel: +82-54-279-2108

b Department of Molecular Medicine and Nuclear Medicine, College of Medicine, Kyungpook National University, Joong-gu, Daegu, South Korea

c Department of Surgery, College of Medicine, Kyungpook National University, Dong-In, Joong-gu, Daegu 700-422, South Korea

d KRICT-EPFL Global Research Laboratory, Advanced Materials Division, Korea Research Institute of Chemical Technology, 19 Sinseongno, Yuseong, Daejeon 305-600, Republic of Korea

e BioNano Research Center, Korea Research Institute of Bioscience and Bioengineering, Yuseong-gu, Daejeon 305-806, South Korea

Abstract

A new multiplexed NIR in vivo imaging is showcased by using quantum dots and NaYF4:Yb3+,Tm3+ nanoparticles. The ‘temporal’ multiplexing is demonstrated by alternating the excitation wavelengths and unmixing the emissions of different probes. Multiplexed cellular imaging and the cellular trafficking in animal models are shown.

Graphical abstract: Multiplexed near-infrared in vivo imaging complementarily using quantum dots and upconverting NaYF4:Yb3+,Tm3+ nanoparticles

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Article information

DOI
https://doi.org/10.1039/C1CC12746B
Article type
Communication
Submitted
10 May 2011
Accepted
27 May 2011
First published
10 Jun 2011

Chem. Commun., 2011,47, 8022-8024

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Multiplexed near-infrared in vivo imaging complementarily using quantum dots and upconverting NaYF4:Yb3+,Tm3+ nanoparticles

S. Jeong, N. Won, J. Lee, J. Bang, J. Yoo, S. G. Kim, J. A. Chang, J. Kim and S. Kim, Chem. Commun., 2011, 47, 8022 DOI: 10.1039/C1CC12746B

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