Issue 33, 2011
From the journal:

Chemical Communications

Resonance light scattering as a powerful tool for sensitive detection ofβ-amyloid peptide by gold nanoparticle probes†

Chengke Wang,ab   Dianjun Liua  and  Zhenxin Wang*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: wangzx@ciac.jl.cn
Tel: +86 431 85262243

b Graduate School of the Chinese Academy of Sciences, Beijing, China

Abstract

A novel biosensing strategy has been developed for sensitive detection of β-amyloid 1–42 (Aβ1–42) down to the ng mL−1 level in both aqueous solution and diluted human plasma, which is based on measuring changes in resonance light scattering of streptavidin functionalized gold nanoparticles as a function of the concentration of Aβ1–42 with a conventional spectrofluorometer.

Graphical abstract: Resonance light scattering as a powerful tool for sensitive detection ofβ-amyloid peptide by gold nanoparticle probes

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Article information

DOI
https://doi.org/10.1039/C1CC12939B
Article type
Communication
Submitted
19 May 2011
Accepted
28 Jun 2011
First published
15 Jul 2011

Chem. Commun., 2011,47, 9339-9341

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Resonance light scattering as a powerful tool for sensitive detection ofβ-amyloid peptide by gold nanoparticle probes

C. Wang, D. Liu and Z. Wang, Chem. Commun., 2011, 47, 9339 DOI: 10.1039/C1CC12939B

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