Issue 31, 2011
From the journal:

Chemical Communications

A photoinduced pH jump applied to drug release from cucurbit[7]uril†

Cátia Parente Carvalho,a   Vanya D. Uzunova,b   José P. Da Silva,c   Werner M. Naub  and  Uwe Pischel*a  

* Corresponding authors

a Centro de Investigación en Química Sostenible and Departamento de Ingeniería Química, Química Física y Química Orgánica, Universidad de Huelva, Campus de El Carmen s/n, E-21071 Huelva, Spain
E-mail: uwe.pischel@diq.uhu.es
Fax: +34 959 21 99 83
Tel: +34 959 21 99 82

b School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759 Bremen, Germany

c CIQA-Faculdade de Ciências e Tecnologia, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal

Abstract

A proof-of-principle for the application of a photoinduced pH jump for delivery of the Hoechst 33258 drug by disassembly of its host–guest complex with cucurbit[7]uril is described.

Graphical abstract: A photoinduced pH jump applied to drug release from cucurbit[7]uril

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Article information

DOI
https://doi.org/10.1039/C1CC12954F
Article type
Communication
Submitted
19 May 2011
Accepted
22 Jun 2011
First published
07 Jul 2011

Chem. Commun., 2011,47, 8793-8795

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A photoinduced pH jump applied to drug release from cucurbit[7]uril

C. P. Carvalho, V. D. Uzunova, J. P. Da Silva, W. M. Nau and U. Pischel, Chem. Commun., 2011, 47, 8793 DOI: 10.1039/C1CC12954F

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