Issue 38, 2011
From the journal:

Chemical Communications

Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging†

Sara Figueiredo,ab   João Nuno Moreira,c   Carlos F. G. C. Geraldes,a   Silvia Rizzitelli,b   Silvio Aimeb  and  Enzo Terreno*b  

* Corresponding authors

a Department of Life Sciences, Faculty of Sciences and Technology, and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal

b Department of Chemistry IFM and Molecular & Preclinical Imaging Centers, University of Torino, Via Nizza, 52, Torino, Italy
E-mail: enzo.terreno@unito.it
Fax: +39-0116706487
Tel: +39-0116706452

c Laboratory of Pharmaceutical Technology, Faculty of Pharmacy and Center for Neurosciences and Cell Biology, University of Coimbra, Portugal

Abstract

This communication demonstrates that yeast cell wall particles (YCWPs) are a promising class of nature-inspired biocompatible microcarriers for the delivery of amphipathic/lipophilic imaging reporters. When a paramagnetic MRI agent is loaded, the longitudinal relaxivity per particle at 0.5 T is the highest ever reported for Gd-based systems.

Graphical abstract: Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging

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Article information

DOI
https://doi.org/10.1039/C1CC14019A
Article type
Communication
Submitted
05 Jul 2011
Accepted
17 Aug 2011
First published
01 Sep 2011

Chem. Commun., 2011,47, 10635-10637

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Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging

S. Figueiredo, J. N. Moreira, C. F. G. C. Geraldes, S. Rizzitelli, S. Aime and E. Terreno, Chem. Commun., 2011, 47, 10635 DOI: 10.1039/C1CC14019A

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