Issue 41, 2011
From the journal:

Chemical Communications

Fluorescent DNA chemosensors: identification of bacterial species by their volatile metabolites†

Chi-Kin Koo,a   Shenliang Wang,a   Rajiv L. Gaur,b   Florent Samain,a   Niaz Banaeib  and  Eric T. Kool*a  

* Corresponding authors

a Department of Chemistry, Stanford University, Stanford, California 94305, USA
E-mail: kool@stanford.edu
Fax: +1 650 725 0259
Tel: +1 650 724 4741

b Department of Pathology, Stanford University School of Medicine, Palo Alto, California 94304, USA

Abstract

Polyfluorophores built on a DNA scaffold (ODFs) were synthesized and tested for fluorescence responses to the volatiles from M. tuberculosis, E. coli and P. putida in closed Petri dishes. Two sensors in a pattern-based response could distinguish the bacterial strains accurately, suggesting the use of ODFs in rapid identification of infectious agents.

Graphical abstract: Fluorescent DNA chemosensors: identification of bacterial species by their volatile metabolites

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Article information

DOI
https://doi.org/10.1039/C1CC14871K
Article type
Communication
Submitted
07 Aug 2011
Accepted
06 Sep 2011
First published
21 Sep 2011

Chem. Commun., 2011,47, 11435-11437

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Fluorescent DNA chemosensors: identification of bacterial species by their volatile metabolites

C. Koo, S. Wang, R. L. Gaur, F. Samain, N. Banaei and E. T. Kool, Chem. Commun., 2011, 47, 11435 DOI: 10.1039/C1CC14871K

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