Issue 48, 2011
From the journal:

Chemical Communications

Target recycling amplification for sensitive and label-free impedimetric genosensing based on hairpin DNA and graphene/Au nanocomposites†

Ying Chen,a   Bingying Jiang,b   Yun Xiang,*a   Yaqin Chaia  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

b School of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400054, P. R. China

Abstract

The presence of exonuclease III leads to direct recycling and reuse of the target DNA, which in turn results in substantial signal amplification for highly sensitive, label-free impedimetric detection of specific DNA sequences.

Graphical abstract: Target recycling amplification for sensitive and label-free impedimetric genosensing based on hairpin DNA and graphene/Au nanocomposites

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Article information

DOI
https://doi.org/10.1039/C1CC14902D
Article type
Communication
Submitted
08 Aug 2011
Accepted
27 Oct 2011
First published
11 Nov 2011

Chem. Commun., 2011,47, 12798-12800

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Target recycling amplification for sensitive and label-free impedimetric genosensing based on hairpin DNA and graphene/Au nanocomposites

Y. Chen, B. Jiang, Y. Xiang, Y. Chai and R. Yuan, Chem. Commun., 2011, 47, 12798 DOI: 10.1039/C1CC14902D

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