Cytotoxic potency of small macrocyclic knot proteins: Structure–activity and mechanistic studies of native and chemically modified cyclotides†
Abstract
The cyclotides are a family of circular and knotted
* Corresponding authors
a
Division of Pharmacognosy, Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, Uppsala, Sweden
E-mail:
ulf.goransson@fkog.uu.se
Fax: +46-18-509101
Tel: +46-18-4715031
b College of Pharmacy, University of Michigan, Ann Arbor, MI, USA
c Division of Clinical Pharmacology, Department of Medical Sciences, University Hospital, Uppsala University, Uppsala, Sweden
The cyclotides are a family of circular and knotted
R. Burman, A. Herrmann, R. Tran, J. Kivelä, A. Lomize, J. Gullbo and U. Göransson, Org. Biomol. Chem., 2011, 9, 4306 DOI: 10.1039/C0OB00966K
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