Issue 7, 2011
From the journal:

Organic & Biomolecular Chemistry

First total synthesis of Papilistatin†

Meng Wu,a   Ling Li,a   An-Zheng Feng,a   Bo Su,a   De-min Liang,a   Yu-xiu Liua  and  Qing-min Wang*a  

* Corresponding authors

a State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, People's Republic of China
E-mail: wang98h@263.net
Fax: +86-22-23499842

Abstract

Papilistatin has been isolated recently and found to have good anticancer and antibacterial activity. Papilistatin is a unique phenanthrene-1,10-dicarboxylic acid. The first total synthesis of papilistatin is described here with radical cyclisation as the key step.

Graphical abstract: First total synthesis of Papilistatin

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Article information

DOI
https://doi.org/10.1039/C0OB01214A
Article type
Paper
Submitted
20 Dec 2010
Accepted
25 Jan 2011
First published
26 Jan 2011

Org. Biomol. Chem., 2011,9, 2539-2542

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First total synthesis of Papilistatin

M. Wu, L. Li, A. Feng, B. Su, D. Liang, Y. Liu and Q. Wang, Org. Biomol. Chem., 2011, 9, 2539 DOI: 10.1039/C0OB01214A

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