Issue 1, 2011
From the journal:

Soft Matter

Dendrimer-induced DNA bending†

Chun-Yu Chen,a   Chun-Jen Su,b   Shu-Fen Peng,a   Hsin-Lung Chen*a  and  Hsing-Wen Sung*a  

* Corresponding authors

a Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan
E-mail: hlchen@che.nthu.edu.tw, hwsung@che.nthu.edu.tw

b National Synchrotron Radiation Research Center, Hsinchu, Taiwan

Abstract

Depending on the dendrimer charge density (CD), the complexes of DNA with polyamidoamine G4 dendrimer exhibited three distinct nanostructures, characterized by different degrees of DNA bending. With increasing CD, the structure transformed from a square columnar mesophase to hexagonally-packed superhelices and eventually to a beads-on-string structure in which DNA wrapped around the dendrimer by 1.4 turns and penetrated into the dendrimer interior.

Graphical abstract: Dendrimer-induced DNA bending

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Article information

DOI
https://doi.org/10.1039/C0SM00665C
Article type
Communication
Submitted
11 Jul 2010
Accepted
21 Oct 2010
First published
08 Nov 2010

Soft Matter, 2011,7, 61-63

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Dendrimer-induced DNA bending

C. Chen, C. Su, S. Peng, H. Chen and H. Sung, Soft Matter, 2011, 7, 61 DOI: 10.1039/C0SM00665C

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