Issue 10, 2012
From the journal:

Chemical Communications

Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis†‡

Niranjan Kumar Namelikondaa  and  Roman Manetsch*a  

* Corresponding authors

a Department of Chemistry, University of South Florida, 4202 E Fowler Ave., Tampa, FL, USA
E-mail: manetsch@usf.edu
Tel: +1 8139747306

Abstract

Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides.

Graphical abstract: Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

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Article information

DOI
https://doi.org/10.1039/C1CC14724B
Article type
Communication
Submitted
31 Jul 2011
Accepted
15 Aug 2011
First published
05 Sep 2011

Chem. Commun., 2012,48, 1526-1528

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Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

N. K. Namelikonda and R. Manetsch, Chem. Commun., 2012, 48, 1526 DOI: 10.1039/C1CC14724B

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