Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells

Zhiguang Yang; Ning Zhao; Yuming Sun; Fang Miao; Yong Liu; Xin Liu; Yuanhong Zhang; Wentao Ai; Guofen Song; Xiaoyuan Shen; Xiaoqiang Yu; Jingzhi Sun; Wai-Yeung Wong

doi:10.1039/C2CC00093H

Highly selective red- and green-emitting two-photonfluorescent probes for cysteine detection and their bio-imaging in living cells†

Zhiguang Yang,‡^a Ning Zhao,‡^a Yuming Sun,^b Fang Miao,^a Yong Liu,^a Xin Liu,^a Yuanhong Zhang,^a Wentao Ai,^a Guofen Song,^a Xiaoyuan Shen,^c Xiaoqiang Yu,*^a Jingzhi Sun*^c and Wai-Yeung Wong*^d

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* Corresponding authors

^a Center of Bio & Micro/Nano Functional Materials, State Key Lab of Crystal Materials, Shandong University, Jinan 250100, P. R. China
E-mail: yuxq@sdu.edu.cn
Tel: +8653188366418

^b School of Information Science and Engineering, Shandong University, P. R. China

^c Institute of Biomedical Macromolecules, Department of Polymer Science and Engineering, MoE Key Laboratory of Macromolecule Synthesis and Functionalization, Zhejiang University, P. R. China
E-mail: sunjz@zju.edu.cn

^d Institute of Molecular Functional Materials and Department of Chemistry and Institute of Advanced Materials, Hong Kong Baptist University, Hong Kong, P. R. China
E-mail: rwywong@hkbu.edu.hk

Abstract

Two highly selective two-photon fluorescent probes for cysteine over homocysteine, N-acetyl-L-cysteine, dithiothreitol, glutathione and other amino acids, and their fluorescent imaging in living cells have been shown.

Chemical Communications

Highly selective red- and green-emitting two-photonfluorescent probes for cysteine detection and their bio-imaging in living cells†

Abstract

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Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells

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