Issue 13, 2012
From the journal:

Chemical Communications

Enzymatic biofuel cells utilizing a biomimetic cofactor†

Elliot Campbell,a   Matthew Meredith,b   Shelley D. Minteerb  and  Scott Banta*a  

* Corresponding authors

a Department of Chemical Engineering, Columbia University in the City of New York, New York, USA
E-mail: sbanta@columbia.edu
Fax: +1 212 854 3054
Tel: +1 212 854 7531

b Department of Chemistry and Materials Science and Engineering, 315 S 1400 E Room 2020, Salt Lake City, USA
E-mail: minteer@chem.utah.edu

Abstract

The performance of immobilized enzyme systems is often limited by cofactor diffusion and regeneration. Here, we demonstrate an engineered enzyme capable of utilizing the minimal cofactor nicotinamide mononucleotide (NMN+) to address these limitations. Significant gains in performance are observed with NMN+ in immobilized systems, despite a decreased turnover rate with the minimal cofactor.

Graphical abstract: Enzymatic biofuel cells utilizing a biomimetic cofactor

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Article information

DOI
https://doi.org/10.1039/C2CC16156G
Article type
Communication
Submitted
03 Oct 2011
Accepted
24 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 1898-1900

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Enzymatic biofuel cells utilizing a biomimetic cofactor

E. Campbell, M. Meredith, S. D. Minteer and S. Banta, Chem. Commun., 2012, 48, 1898 DOI: 10.1039/C2CC16156G

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