Issue 15, 2012
From the journal:

Chemical Communications

Immobilization-free screening of aptamers assisted by graphene oxide†

Jee-Woong Park,‡a   Rameshwar Tatavarty,‡a   Dae Woo Kim,b   Hee-Tae Jungb  and  Man Bock Gu*a  

* Corresponding authors

a College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-713, South Korea
E-mail: mbgu@korea.ac.kr
Fax: +822-928-6050
Tel: +822-3290-3417

b Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science & Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, South Korea
Fax: +82 42-350-8890
Tel: +82 42-350-3931

Abstract

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

Graphical abstract: Immobilization-free screening of aptamers assisted by graphene oxide

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC16473F
Article type
Communication
Submitted
18 Oct 2011
Accepted
23 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 2071-2073

Permissions

Request permissions

Immobilization-free screening of aptamers assisted by graphene oxide

J. Park, R. Tatavarty, D. W. Kim, H. Jung and M. B. Gu, Chem. Commun., 2012, 48, 2071 DOI: 10.1039/C2CC16473F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements