An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS†
Abstract
An aptamer microarray was directly fabricated on a MALDI target plate for high-throughput insulin detection. High sensitivities were observed both in standard solutions (5 ng mL−1, 0.86 nM) and serum sample (20 ng mL−1, 3.4 nM). This method shows great promise in the field of