Facilitative functionalization of cyanine dye by an on–off–on fluorescent switch for imaging of H2O2 oxidative stress and thiols reducing repair in cells and tissues

Abstract

We presented the design, synthesis, spectroscopy, and biological applications of DA–Cy, an on–off–on fluorescent probe to monitor H₂O₂ oxidative stress and thiols reducing repair in living cells and tissues simply and directly.