A highly efficient catalyst-free protocol for C–H bond activation: sulfamidation of alkyl aromatics and aldehydes

Abstract

A catalyst-free protocol has been developed for amidation of alkyl aromatics and aldehydes using TsNBr₂via a nitrene transfer process in the presence of a base in excellent yield within a short time. The reaction was found to be selective for secondary and tertiary benzylic C–H bonds and C–H bonds of aldehydic groups.