Issue 41, 2012
From the journal:

Chemical Communications

Generation of 4-polyfluoroaryl pyrrolo[1,2-a]quinolines via C–H bond activation†

Shengqing Ye,a   Jianping Liu*b  and  Jie Wu*ac  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China
E-mail: jie_wu@fudan.edu.cn
Fax: +86 21 6564 1740
Tel: +86 21 6510 2412

b EENT Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, China

c State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China

Abstract

A novel and efficient preparation of 4-polyfluoroaryl pyrrolo[1,2-a]quinolines via a palladium-catalyzed reaction of 1-[2-(2,2-dibromoethenyl)phenyl]-1H-pyrrole with polyfluoroarene is described. This transformation is efficient, leading to the corresponding products in good yields.

Graphical abstract: Generation of 4-polyfluoroaryl pyrrolo[1,2-a]quinolines via C–H bond activation

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Article information

DOI
https://doi.org/10.1039/C2CC31301D
Article type
Communication
Submitted
21 Feb 2012
Accepted
22 Mar 2012
First published
23 Mar 2012

Chem. Commun., 2012,48, 5028-5030

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Generation of 4-polyfluoroaryl pyrrolo[1,2-a]quinolines via C–H bond activation

S. Ye, J. Liu and J. Wu, Chem. Commun., 2012, 48, 5028 DOI: 10.1039/C2CC31301D

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